5 or CD45 according to CP 868596 the degree of caries or extent of physiological root resorption (two-way anova, P > 0.05). Findings suggest that even if primary molars are undergoing exfoliation, they show comparable caries-induced changes to teeth without physiological root resorption, thus retaining potential for healing and repair. “
“International Journal of Paediatric Dentistry 2013; 23: 138–144 Background.  Individual calibration (IC) for caries detection methods based on fluorescence is time-consuming, especially for paediatric dentists, if the calibration has to be performed

tooth-by-tooth. However, it is not clear how this calibration actually interfere in laser fluorescence (LF) readings. Aim.  This in vivo study was to verify the influence of different modes of IC on laser fluorescence (LF) readings. Design.  Ninety six occlusal and 95 buccal surfaces of 1st permanent molars were examined using LF device after IC performed on control (no IC), the examined teeth, a permanent incisor, a 1st primary molar or a 2nd primary molar. All modes of IC were performed in the same child. Wilcoxon test and Bland–Altman analysis were used to compare the readings. Intraclass correlation coefficients (ICC) were calculated. Results.  Laser fluorescence readings

without prior calibration were higher than readings performed after any mode of IC and resulted in different values of ICC. After other IC modes, the LF readings were statistically similar. Conclusion.  The absence of IC influences Venetoclax concentration LF readings and LF reproducibility, but different IC methods can be considered in clinical practice. “
“International Journal Thymidylate synthase of Paediatric Dentistry 2011; 22: 44–51 Background.  Despite the efficacy of non-drilling approaches to manage non-cavitated

dentin occlusal lesions (NCDOL) in permanent teeth, there is no data validating this type of therapy in the primary dentition. Aim.  To compare the efficacy of a traditional fissure sealant in managing NCDOL in primary molars. Design.  This study is a randomized controlled clinical trial with a split-mouth design. Thirty schoolchildren with two NCDOL were selected and divided into two groups. The experimental group received a resin-based fissure sealant, whereas the control group was treated with a conventional composite resin. Treatment efficacy was evaluated after 1 year by means of clinical and radiographic examinations. Results.  The two treatment modalities were found to be similarly effective in managing DONCL in primary molars. Conclusion.  For the management of non-cavitated dentin occlusal caries in primary teeth, the invasive approach can be replaced with non-drilling fissure sealing techniques. “
“International Journal of Paediatric Dentistry 2012; 22: 85–91 Background.  In a previous study, 9-year-old children with severe Molar Incisor Hypomineralization (MIH) had undergone dental treatment of their first molars nearly ten times as often as children in a control group.