Infect Immun 2008,76(12):5694–5705.PubMedCrossRef 28. Barthold SW, Moody KD, Terwilliger GA, Duray PH, Jacoby RO, Steere AC: Experimental Lyme arthritis in rats infected with Borrelia burgdorferi. J Infect Dis 1988,157(4):842–846.PubMedCrossRef 29. Chan K, Casjens S, Parveen N: Detection of established virulence genes and plasmids to differentiate Borrelia burgdorferi strains. Infect Immun 2012,80(4)):1519–1529.PubMedCrossRef 30. Schutzer SE, Fraser-Liggett CM, Casjens SR, Qiu WG, Dunn JJ, Mongodin EF, Luft BJ: Whole-genome sequences of thirteen isolates of Borrelia burgdorferi. J Bacteriol 2011,193(4):1018–1020.PubMedCrossRef 31. ATM Kinase Inhibitor research buy Mathiesen
DA, Oliver JH Jr, Kolbert CP, Tullson ED, Johnson BJ, Campbell GL, Mitchell PD, Reed KD, Telford SR, Anderson JF 3rd,
et al.: Genetic heterogeneity of Borrelia burgdorferi in the United States. The Journal of infectious diseases 1997,175(1)):98–107.PubMedCrossRef 32. Wang G, Ojaimi C, Wu H, Saksenberg V, Iyer R, Liveris D, McClain SA, Wormser GP, Schwartz I: Disease severity in a murine model of lyme borreliosis is associated with the genotype of the infecting Borrelia burgdorferi sensu stricto strain. J Infect Dis 2002,186(6):782–791.PubMedCrossRef 33. Wang G, Ojaimi C, Iyer R, Saksenberg V, McClain SA, Wormser GP, Schwartz I: Impact of genotypic variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease EPZ-6438 in C3H/HeJ mice. Infect Immun 2001,69(7):4303–4312.PubMedCrossRef 34. Strle K, Jones KL, Drouin EE, Li X, Steere AC: Borrelia burgdorferi RST1
(OspC type A) genotype is associated with greater inflammation and more severe Lyme disease. Ame J Pathol 2011,178(6):2726–2739.CrossRef 35. Armstrong AL, Barthold SW, Persing DH, Beck DS: Lyme disease susceptible and resistant strains of laboratory mice infected with Borrelia burgdorferi. Amer J Trop Med Hyg 1992, 47:249–258. 36. Barthold SW, Persing DH, Armstrong AL, Peeples RA: Kinetics of Borrelia Cobimetinib burgdorferi dissemination and evolution of disease after intradermal inoculation of mice. Am J Pathol 1991,139(2):263–273.PubMed 37. Cadavid D, Bai Y, Dail D, Hurd M, Narayan K, Hodzic E, Barthold SW, Pachner AR: Infection and inflammation in skeletal muscle from nonhuman primates infected with different genospecies of the Lyme disease spirochete Borrelia burgdorferi. Infect Immun 2003,71(12):7087–7098.PubMedCrossRef 38. Parveen N, Caimano M, Radolf JD, Leong JM: Adaptation of the Lyme disease spirochaete to the mammalian host environment results in enhanced glycosaminoglycan and host cell binding. Mol Microbiol 2003,47(5):1433–1444.PubMedCrossRef 39. Zeidner NS, Nuncio MS, Schneider BS, Gern L, Piesman J, Brandao O, Filipe AR: A portuguese isolate of Borrelia lusitaniae induces disease in C3H/HeN mice. J Med Microbiol 2001,50(12):1055–1060.PubMed 40.