Methods and Results: A total of 130 patients from 3 sites with left ventricular ejection fraction ARN-509 Endocrinology & Hormones inhibitor <= 35% were enrolled during hospitalization for heart failure (HF) and randomly assigned to therapy guided by BNP and clinical assessment (BNP strategy) or clinical assessment alone. The clinical goal was resolution of congestion without hypotension or renal dysfunction. In the BNP arm, therapy was adjusted to achieve optimal fluid status, defined as the BNP level and congestion score obtained at the time of discharge. In

the clinical assessment arm, therapy was titrated to achieve optimal fluid status, represented by the patient’s signs and symptoms at the time of discharge. Exclusion criteria were serum creatinine >3.5 mg/dL and acute coronary syndrome. Follow-up was done in HF clinics. BNP was measured with the use of a rapid assay test. There was no significant difference in number of days alive and not hospitalized

(hazard ratio 0.72, 95% confidence interval 0.41-1.27; P = .25), change in serum creatinine, or change in systolic blood pressure (SBP). BNP strategy was associated with a trend toward a lower blood urea nitrogen (24 mg/dL vs 29 mg/dL; P = .07); BNP strategy patients received significantly more angiotensin converting enzyme (ACE) inhibitors, beta-blockers, and the combination of ACE inhibitor or angiotensin receptor blocker plus beta-blockers.

Conclusions: learn more BNP strategy was not associated with more days alive and not hospitalized, but the strategy appeared to be safe and was associated with increased use of evidence-based medications. (J Cardiac Fail 2011;17:613-621)”
“Magnetic

properties, phase constitution, and microstructure of melt spun R-lean and B-enriched Mischmetal (MM)-Fe-Co-Ti-B nanocomposites have been investigated. The thermal magnetic analysis show that only 2:14:1 and alpha-Fe [alpha-(Fe, Co)] phases appear for MM(A)(9.5)Fe(78.5)Ti(2)B(10) and MM(A)(9)Fe(79.5)Co(2.5)Ti(1)B(8) Adavosertib ribbons, while an additional Fe(3)B phase is present for R(9.25)Fe(79.25)Co(2.5)Ti(1)B(8) [R=MM(A), MM(B), and MM(C)] ribbons. The magnetic properties of the above nanocomposites are determined not only by the phase constitution of MM-Fe-Co-Ti-B nanocomposites but also by the composition of MMs. Besides, fine grain size of 15-40 nm is almost unchanged for the ribbons with various MMs, giving rise to the strong exchange coupling effect between magnetic grains and the improved magnetic performance. In this study, the optimum magnetic properties of B(r) = 9.6 kG, (i)H(c)= 8.6 kOe, and (BH)(max) = 18.2 MG Oe can be achieved for MM(B)(9.25)Fe(79.25)Co(2.5)Ti(1)B(8) nanocomposites. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.

(J Cardiac Fail 2011;17:151-157)”
“The influence of the Mn substitution by Fe atoms on the magnetocaloric and magnetic properties AC220 of the martensitic Ni(50)Mn(36)Sn(14) Heusler-type compound has been investigated using magnetization measurements. The insertion of Fe atoms reduces the Mn-Mn AF interactions resulting in (i) a systematic

decrease in the martensitic transition temperature, down to its disappearance at 15 at. % of Fe, (ii) an enhancement of the saturation magnetization, and (iii) a monotonic increase in the L2(1)-type phase Curie temperature. The Fe substitution also induces metamagnetic transition from an incipient AF to a noncollinear spin configuration for applied magnetic fields higher Selleckchem Mocetinostat than 3 T in the case of 3 and 7 at. % Fe substitutional. The exchange-bias effect is only found in compounds with a well-defined martensitic phase transition (Fe content lower than 10 at. %). The maximum of the inverse magnetic entropy change, for a field variation of 5 T, is about +12 J kg(-1) K(-1) and it is nearly constant for Fe content up to 7 at. %. This observation suggests that the Ni(50)(Mn(1-x)Fe(x))(36)Sn(14) Heusler-type compounds could be used to prepare composites with potential for technological application in magnetic refrigerators.”
“Colon cancer is one of the major causes of cancer mortality worldwide. The analysed feeds, containing non-genetically modified

(GM) soybean and Roundup Ready soybean, showed a different

polyphenolic content and lipophilic composition. Non-GM soybean extract possessed twice the polyphenolic content of GM soybean and the highest number of sterols. Among them, -sitosterol was found to be the major constituent. Methanolic extract of non-GM soybean extract was more potent than GM soybean extract against colon carcinoma cell line LoVo using MTT assay, while the second MEK inhibitor review one showed a slightly higher anti-inflammatory activity. The findings add to epidemiological evidence for the therapeutic effects of soy foods in colorectal carcinoma.”
“Heart failure with preserved ejection fraction (HFpEF) is a substantial public health issue, equal in magnitude to heart failure with reduced ejection fraction. Clinical outcomes of HFpEF patients are generally poor, related annual accrual of health care expenses amount to billions of dollars, and no therapy has been shown to be effective in randomized clinical trials. Baroreflex activation therapy (BAT) produced by stimulating the carotid sinuses using an implanted device (Rheos) is being studied for the treatment of hypertension, the primary comorbidity of HFpEF. Other potential benefits include regression of left ventricular hypertrophy, normalization of the sympathovagal balance, inhibition of the renin-angiotensin-aldosterone system, arterio- and venodilation, and preservation of renal function.

The mean hepatocyte-phase SI ratio of HCCs (0.65 +/- 0.14 [ standard deviation]) was significantly lower (P < .01) than that of the nodular pseudolesions (0.95 +/- 0.11). The optimal cutoff value of hepatocyte-phase

SI ratio for distinguishing between HCC and nodular pseudolesion was 0.84. No nodular pseudolesions were visible on DW images.

Conclusion: Gadoxetic acid-enhanced hepatocyte-phase MR imaging and DW imaging could be used to distinguish hypervascular pseudolesions from hypervascular HCCs; a hepatocyte-phase SI ratio below 0.84 and visibility on DW images were findings specific for HCCs rather than pseudolesions. (C) RSNA, 2010″
“The aim of the study was to LY3023414 mw explore the association between the FK228 severity of psychosomatic symptoms and perceived work stress among male

police officers in southern Taiwan. By stratified random sampling, a total of 698 male police officers were recruited into this study (the response rate was 73.4%; 512 of 698). A structured self-administered questionnaire on demographic and working characteristics, the severity of psychosomatic symptoms, perceived work stress, and social support was used to collect data anonymously. The results of multiple regression analysis revealed that (1) the police officers who perceived high-work stress reported more severe psychosomatic symptoms than those who perceived low-work stress; and (2) perceived social support had a moderating effect on the association between severity of psychosomatic symptoms and perceived work stress. Perceived work stress is an indicator of psychosomatic symptoms in police

officers. Strategies for reducing psychosomatic symptoms of police officers include police CUDC-907 administrators taking into account the level of work stress as well as more attention being paid to the resources of social support.”
“In this study, we present the experimental results for the crosslinking process of a commercial polyester resin based on measurements of the spin lattice relaxation time T-1 of protons, as function of the crosslinking time evolution. Multiexponential decomposition of the evolution of magnetization measured in inversion-recovery experiments is performed. The population of “”rigid” and “”mobile” nuclear spin sites was estimated as function of time evolution. In analogy to the usual monomer conversion u, site conversion from “”mobile” to “”rigid” sites u(M) were also estimated as a function of time evolution and initial concentrations of the reagents. The multiexponential decomposition approach of T-1 relaxation data allows one to follow crosslinking processes. (C) 2011 Wiley Periodicals, Inc.

All rights reserved.”
“We report novel results on optimization of intercalated polymer-clay nanocomposite endowed with desirable properties like, (i) very high ionic conductivity similar to 10(-3) S cm(-1)) at room temperature, (ii) substantial improvement in voltage stability (similar to 5.6 V), mechanical stability (25 MPa), and thermal stability (250 degrees C) (iii) t(ion) similar to 99% and cation transport number (t(Li+)) similar to 67%: Intercalation of polymer salt (PAN)(8)LiCF(3)SO(3) complex into dodecylamine

modified montmorillonite clay (DMMT) nanometric channels has been confirmed by X-ray diffraction and Transmission electron microscopy analysis. Complex impedance spectroscopy suggests bulk electrical conduction in the high Mcl-1 apoptosis frequency region and electrode polarization effect at the low frequencies. The experimental value of conductivity, voltage, and mechanical stability is observed to be invariably higher in polymer nanocomposite film when compared with clay free polymer-salt complex film. The same is true for cation transport. The optimized polymer film serves dual purpose of electrolyte and separator in energy storage devices. (C) 2010 Wiley Periodicals, Inc. J Appl Polyrn Sci 118: 2743-2753, 2010″
“IgG subclass levels of sera from 105 patients with systemic lupus erythematosus

(SLE) were determined by immunonephelometric assay. Patients were divided into two groups Vactosertib concentration according to clinical activity of the disease: active disease and remission. Forty-five normal controls were also measured. We found a significant increase of IgG1 (p = 0.000), IgG2 (p = 0.000), and IgG3 (p = 0.000) in SLE sera, while IgG4 (p = 0.494) values did not differ significantly from those of

controls. When patients were divided according to clinical activity, decrease of IgG3 concentration was observed in the patients in remission. In contrast, the concentrations of IgG1, IgG2, and IgG4 subclass were similar between the two groups (p > 0.05). Our data suggest that differential increase of IgG subclasses during the course of SLE may be of relevance to the pathogenesis of the disease.”
“Background: QNZ supplier Hepatitis C virus (HCV) infection prevalence among young injection drug users (IDUs) differs substantially between cities in the United States (U.S.).

Methods: Between 2002 and 2004. IDUs aged 15-30 were recruited for the Third Collaborative Injection Drug User Study in five U.S. cities using respondent-driven methods. Our cross-sectional study examined correlates and geographic distribution of prevalent HCV infection (HCV+) from the Baltimore (n = 736) and Chicago (n = 586) study sites. We evaluated baseline socio-demographic and behavioral data collected from computer-assisted self-interviews and serological antibody testing for human immunodeficiency virus (HIV) and hepatitis A, B, and C.

Results: HCV prevalence was 53.0% in Baltimore and 13.7% in Chicago (p < 0.0001).

VEGF gene polymorphisms were assessed with PCR-RFLP analysis of DNA samples obtained from leukocytes. DNA fragments were investigated by using appropriate primers. SNP scanning was performed using MnII, BgIII, BshI2361, Hsp92II restriction enzymes for 1154 G/A, 2578 C/A, 460 C/T, and 936 C/T polymorphisms, respectively. The frequencies of 2578 C/A, 460 C/T,

936 C/T polymorphisms were not significantly different between the controls and women with recurrent pregnancy loss. However, the prevalence of the 1154 G/A polymorphism A/A genotype was significantly higher in the recurrent pregnancy click here loss group (23.7 vs 3.4%). One of the four common polymorphisms of the VEGF gene was found to be more frequent in women with recurrent pregnancy loss. It is possible that disruption of VEGF function and placental angiogenesis can contribute to pregnancy loss in women with recurrent pregnancy loss.”
“Gestational malaria Poziotinib price is a multi-factorial syndrome leading to poor outcomes for both the mother

and foetus. Although an unusual increasing in the number of hospitalizations caused by Plasmodium vivax has been reported in Brazil, mortality is rarely observed. This is a report of a gestational malaria case that occurred in the city of Manaus (Amazonas State, Brazil) and resulted in foetal loss. The patient presented placental mixed-infection by Plasmodium vivax and Plasmodium falciparum after diagnosis by nested-PCR, however microscopic analysis failed to detect P. falciparum in the peripheral blood. Furthermore, as the patient did not receive proper treatment for P. falciparum and hospitalization occurred soon after drug

treatment, it seems that P. falciparum pathology was modulated by the concurrent presence of P. vivax. Collectively, this case confirms the tropism towards the placenta by both of these species of parasites, reinforces the notion that co-existence of distinct malaria parasites interferes on diseases’ outcomes, and opens discussions regarding diagnostic Napabucasin methods, malaria treatment during pregnancy and prenatal care for women living in unstable transmission areas of malaria, such as the Brazilian Amazon.”
“Interkeukin-8 (IL-8) is an important inflammatory mediator. It is an angiogenic factor associated with inflammation and carcinogenesis. To date, research on IL-8 has been limited to its role as an indicator of inflammation. There has been no systematic research concerning IL-8 expression levels in the mouse mammary gland during pregnancy and lactation. Mouse mammary gland samples were collected on days 1, 6, 12, 18 of pregnancy and of lactation (6 mice per group). The expression levels of IL-8 mRNA were measured by semi-quantitative RT-PCR, with GAPDH as an internal control. IL-8 mRNA was highly expressed on day 1 of pregnancy in the mouse mammary glands (IL-8(IOD)/GAPDH(IOD) = 1.68), and then suddenly declined; it reached 0.74 and 0.

Experiencing difficulty obtaining the method contributes to high rates of discontinuation. (Obstet Gynecol 2013;121:330-6) DOI: http://10.1097/AOG.0b013e31827e5898″
“BACKGROUND: Bio-ethanol production from renewable sources, such as sugar cane, makes it a biofuel that is both renewable and environmentally friendly. One of the strategies to reduce production costs and to make ethanol fuel economically competitive with fossil fuels could be the use of wild yeast with osmotolerance, ethanol resistance and low nutritional requirements. The aim

of this work was to investigate the kinetics of ethanol fermentation using Saccharomyces cerevisiae ITV-01 yeast strain in a batch system at different glucose and ethanol concentrations, pH values Selleck CT99021 and temperature in order to determine the optimum fermentation

conditions.

RESULTS: This strain showed osmotolerance P5091 chemical structure (its specific growth rate (mu(max)) remained unchanged at glucose concentrations between 100 and 200 g L(-1)) as well as ethanol resistance (it was able to grow at 10% v/v ethanol). Activation energy (Ea) and Q(10) values calculated at temperatures between 27 and 39 degrees C, pH 3.5, was 15.6 kcal mol(-1) (with a pre-exponential factor of 3.8 x 10(12) h(-1) (R(2) = 0.94)) and 3.93 respectively, indicating that this system is biologically limited.

CONCLUSIONS: The optimal conditions for ethanol production were pH 3.5, 30 degrees C and initial glucose concentration 150 g L(-1). In this SYN-117 supplier case, a maximum ethanol concentration of 58.4 g L(-1), ethanol productivity of 1.8 g L(-1) h(-1) and ethanol yield of 0.41 g g(-1) were obtained. (C) 2010 Society of Chemical Industry”
“OBJECTIVE: Cervical cancer is the most common solid carcinoma diagnosed during pregnancy; obviously, pregnancy adds complexity to treatment recommendations. We synthesized all available data and evaluated the efficacy and safety of the administration of platinum derivatives during pregnancy in cervical cancer.

DATA SOURCES: Eligible articles were identified by a search of MEDLINE and ClinicalTrials.gov databases

for the period up to September 7, 2012; the algorithm comprised a predefined combination of the terms “”cervical,”" “”cancer,”" “”cisplatin,”" carboplatin,”" and “”pregnancy.”"

METHODS OF STUDY SELECTION: Two investigators, working independently, searched the literature and extracted data from all studies that examined the efficacy and safety of platinum derivatives administered during pregnancy in cervical cancer. All cases in which therapeutic abortion was scheduled were excluded. Moreover, quantitative synthesis of the published articles was performed.

TABULATION, INTEGRATION, AND RESULTS: Overall, 24 studies (48 pregnancies, 48 newborns [one twin pregnancy and one miscarriage]) were eligible.

Here we report the bipolar doping of GaN1-xAsx with high As content to conductivities above 4 S/cm at room temperature using Mg or Te. The carrier type was confirmed

by thermopower measurements. Doping requires an increase in Ga flux during growth resulting in a mixed phase material of polycrystalline GaAs:N embedded in amorphous GaN1-xAsx. VC 2011 American Institute of Physics. [doi: 10.1063/1.3657779]“
“Since prostate growth is governed by the androgen signaling pathway, blockade of the pathway Momelotinib price is regarded as an appropriate strategy for the treatment of benign prostatic hyperplasia (BPH). Panax ginseng is known to have various pharmacological activities. Of several products of its root, red ginseng, having many bioactive ginsenosides, is most popularly used in Korea, and recently has been reported to control the proliferation of cancer cells. We here tested the effect selleck of a water extract of Korean red ginseng (WKRG) on testosterone-induced prostate hyperplasia. WKRG (daily intraperitoneal injection) prevented prostate overgrowth and epithelial thickening induced by testosterone in rats, and suppressed a rat prostate kallikrein-S3. In human prostate cells, WKRG inhibited testosterone-induced cell proliferation, arrested cell cycle by inducing p21 and p27, and induced apoptosis. Testosterone-induced expression

of human kallikrein-3 mRNA and activation of androgen receptor (AR) were effectively inhibited by WKRG. Of the major ginsenosides included in WKRG, 20(S)-Rg3 was identified to repress AR activity and to attenuate prostate cell growth during testosterone stimulation. Moreover, 20(S)-Rg3 downregulated AR by facilitating the degradation of AR protein. WKRG and 20(S)-Rg3 were found to have new pharmacological activities against testosterone-induced prostate overgrowth. Given that red ginseng has been used safely in Asia for 1000 years, red selleck chemical ginseng and 20(S)-Rg3 could be potential therapeutic regimens for treating BPH.”
“Over

the last 20 years, nearly 5000 cases of differentiated thyroid cancer have been diagnosed and treated in the regions of Russia, Ukraine and Belarus in young people previously exposed to the Chernobyl radioactive fallout during childhood. At diagnosis, 60-70% of the Chernobyl-related paediatric thyroid cancers had clinically evident cervical lymph node metastases (N1) and 10-15% had distant metastases (M1). Despite early reports suggesting that the paediatric thyroid cancer cases that developed after exposure to Chernobyl fallout were particularly aggressive, it now seems that the initial presentation and early clinical course of most of these cases are very similar to both non-radiation-associated paediatric thyroid cancers and thyroid cancers that arise after exposure to external beam irradiation.

“
“SETTING: Tuberculous meningitis (TBM) 10058-F4 datasheet is a severe complication of tuberculosis (TB) predominantly affecting young children. Early initiation of treatment is important to prevent morbidity and mortality

associated with TBM, emphasising the importance of early diagnosis. Among the most promising new methods for diagnosing TB are antigen-detection assays based on the detection of lipoarabinomannan (LAM).

OBJECTIVE: To evaluate the diagnostic value of a commercial, antigen-capture enzyme-linked immunosorbent assay (ELISA) test based on the detection of LAM in urine for the early diagnosis of TBM in children.

METHOD: A cross-sectional study in which urine samples from paediatric patients with suspected TBM attending the Tygerberg Children’s Hospital, Cape Town, South Africa, were tested for LAM.

RESULTS: Complete data were available for 50 of 56 patients with suspected selleck chemicals TBM. TBM was diagnosed

in 21 (42%) patients and excluded in 29 (58%). The LAM ELISA had a sensitivity of 4.8% and a specificity of 93.1%. Serial measurements in the first 2 weeks after treatment initiation did not improve test performance.

CONCLUSION: We have shown that urinary LAM detection was of little value for the diagnosis of TBM in a cohort of paediatric patients with suspected TBM.”
“Background: Genotype-phenotype correlations for chromosomal imbalances are often limited by overlapping effects of partial trisomy Captisol chemical structure and monosomy resulting from unbalanced translocations and by poor resolution of banding analysis for breakpoint designation. Here we report the clinical features of isolated

partial trisomy 7q21.2 to 7q31.31 without overlapping phenotypic effects of partial monosomy in an 8 years old girl. The breakpoints of the unbalanced rearranged chromosome 7 could be defined precisely by array-CGH and a further imbalance could be excluded. The breakpoints of the balanced rearranged chromosomes 9 and 10 were identified by microdissection of fluorescence labelled derivative chromosomes 9 and 10.

Results: The proband’s mother showed a complex balanced translocation t(9;10)(p13;q23) with insertion of 7q21.2-31.31 at the translocation breakpoint at 9p13. The daughter inherited the rearranged chromosomes 9 and 10 but the normal chromosome 7 from her mother, resulting in partial trisomy 7q21.2 to 7q31.31. The phenotype of the patient consisted of marked developmental retardation, facial dysmorphism, short stature, strabism, and hyperextensible metacarpophalangeal joints.

Discussion: For better understanding of genotype-phenotype correlation a new classification of 7q duplications which will be based on findings of molecular karyotyping is needed. Therefore, the description of well-defined patients is valuable. This case shows that FISH-microdissection is of great benefit for precise breakpoint designation in balanced rearrangements.

(C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 3244-3252, 2011″
“Background: Insecticide-treated nets (ITNs) have been confirmed to be a very effective tool in malaria control. Two different delivery strategies for INCB024360 chemical structure roll-out of ITN programmes have been the focus of debate in the last years: free distribution and distribution through commercial marketing systems. They are now seen as complementary rather than opponent. Acceptance of these programmes by the community and involved providers is an important aspect influencing their sustainability. This paper looks at how providers perceived, understood and accepted two

interventions involving two different delivery strategies (subsidized sales supported by social marketing and free distribution to pregnant women attending antenatal care services).

Methods: The interventions took place in one province of north-western Burkina Faso in 2006

in the frame of a large randomized controlled ITN intervention study. For this descriptive qualitative study data were collected through focus group discussions and individual interviews. A total of four focus group discussions and eleven individual interviews have been conducted with the providers of the study interventions.

Results: The free distribution intervention was well accepted and perceived as running well. The health care staff had a positive and beneficial view of the intervention and did not feel overwhelmed by the additional workload. The social marketing intervention was also AZD9291 in vitro seen as positive by the rural shopkeepers. However, working in market economy, shopkeepers feared the risk of unsold ITNs, due to the low demand and capacity to pay for the product in the

community.

Conclusion: The combination of ITN free distribution and social marketing was in general well accepted by the different providers. However, low purchasing power of clients and the resulting financial insecurities of shopkeepers remain a challenge to ITN social marketing in rural SSA.”
“‘The https://www.selleckchem.com/products/ly333531.html green leaf or, to be more precise, the microscopic green grain of chlorophyll, is the focus, the point in the world to which solar energy flows on one side while all the manifestations of life on earth take their source on the other side.’

Kliment Arkadievich Timiryazev The conclusions of a century of plant physiology, speech at Moscow University, 12 January 1901.”
“Fibers produced by melt spinning of conductive polymer composites are attractive for several applications; the main drawback is however reduced processability at high filler concentrations. Carbon nanotubes (CNTs) are considered suitable fillers for conductive polymer composites, replacing conductive grades of carbon black (CB). In this study, the fiber-forming properties of conductive polymer composites based on a conductive grade of CB and two masterbatches with CNT in a polyethylene matrix were investigated. The CB was also used in a polypropylene matrix for comparison.

For this study, self-reported information about the assessment of the patients’ health history and the dentists’ activities with regard to the initial and recall appointments of younger compared with older patients were evaluated. The dentists’ evaluation of the health history showed a clear focus on tobacco in contrast to alcohol. Dentists’ opinions and practices in routine oral examination showed interesting discrepancies. Sixty-five percent, 94%, of the dentists agreed that

this examination for younger (18-39 years) and older www.selleckchem.com/products/dibutyryl-camp-bucladesine.html patients (>= 40 years) should be provided annually. But, only 25%, 30%, of the dentists always examined their younger and older patients at the initial appointment. Approximately 20%, less than 30% always investigated younger and older patients at the recall appointment. The results emphasized a discrepancy in the dentists’ assessments of the health history. Dentists’ opinions about the ACY-738 routine examination differed considerably from the actual integration in the daily work. These findings underline the need for the implementation of targeted educational programmes with focus on primary and secondary prevention. European Journal of Cancer Prevention 20:313-319 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.”
“Oral Diseases (2012) 18, 778785 Objective: The aim of this study was to evaluate the presence and distribution

of CD1a and S100 protein markers in states of gingival health and chronic periodontitis in human subjects. Materials and Methods: Gingival tissue samples were derived from 10 healthy and 10 chronic periodontitis-affected human subjects. The presence

and distribution of CD1a and S100 protein was assessed using immunohistochemistry, and the cell types involved in their expression was determined. Results: The presence and distribution of CD1a was confined only to the gingival epithelium, whereas S100 was seen in the epithelium and connective GDC-0973 purchase tissue. However, increased expression of both CD1a and S100 protein was seen in periodontitis-affected gingival tissues compared with healthy gingiva. Immunohistochemistry demonstrated that CD1a- and S100-positive cells in the epithelium are Langerhans cells (LCs) and S100 positive cells in the connective tissue are dendritic cells (DCs). Conclusion: Our findings suggest the transition of CD1a-positive LCs to S100-positive DCs from epithelium to connective tissue in response to an antigenic challenge. Demonstration of increased number of S100-positive DCs in the gingival connective tissue in chronic periodontitis possibly suggests their involvement in bone resorption in addition to their antigen presentation property.”
“Glycerol can be used as a primary carbon source by yeasts, little is known regarding glycerol metabolism in Candida tropicalis. In this study, glycerol kinase gene (gk) was disrupted from xylitol dehydrogenase gene (XYL2) knockout C. tropicalis strain BSXDH-3. The resultant gk knockout C.