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“Fenpropathrin, a synthetic pyrethroid widely used as an insecticide, is known to affect locomotion and memory in mammals. It is possible that exposure to pyrethroids may occur in an elderly population where transient ischemic attacks are a higher risk for occurrence with consequent changes in memory and control of movement. Thus, the aim of this study was to determine whether bilateral clamping of carotid

arteries (BCCA), a model for ischemia, together with fenpropathrin affected memory in tests such as the passive avoidance task and fresh spatial memory in a Y-maze, as well as movement activity and movement coordination on a rotarod in mice. Danusertib cell line BCCA together with fenpropathrin significantly reduced latency in a passive avoidance task compared to controls. There were no significant differences among the groups with respect to the Y-maze, movement activity, or movement coordination. In conclusion, fenpropathrin needs to be used with caution in the presence of an elderly population at risk for ischemia, as there appears to be evidence of some memory loss in mice.”
“The effect of a dried egg white dietary supplement (2%) on cadmium distribution was examined within 32 d post dosing in the

carcass, liver, kidneys, testes, and thigh muscles of male Wistar rats administered cadmium chloride daily, orally for 28 d at a dose corresponding this website to 10 mg/Cd/kg of feed. Rats fed the egg white protein-supplemented diet displayed markedly higher carcass Cd retention than animals given a standard diet. Further, the protein-supplemented diet increased significantly hepatic Cd retention at 12 h and 4 d, and renal metal retention at 12 h until d 16. In contrast, testicular and thigh-muscle Cd retention already was significantly lower in the rats fed the

egg white protein supplemented diet compared to rats on a standard diet. Higher carcass, hepatic, and renal Cd concentrations were accompanied by greater body weight gains. Taken together, the results of this study showed that increased egg white dietary protein levels enhanced Cd retention in carcass, liver, and kidneys but lowered the metal concentrations in thigh muscles and testes. Data indicate that body weight gains in rats supplemented with egg white proteins exerted tissue-specific effects with respect to Cd accumulation. The potential toxic risk of Cd burden in testes was diminished due to lower metal levels in rats on a protein-supplemented diet. However, this may not be the case in liver and kidneys, as Cd concentrations rose in presence of protein supplementation.”
“Mercury (Hg) is a highly toxic metal posing a hazard to water ecosystems. This investigation was aimed at determining Hg content in the Tanew River, Poland, and subsequent transfer to fish inhabiting this lake. The area studied included approximately a 50-km distance of the river, with 5 sampling locations selected.