Indeed, multifarious cell processes depend on specific recognition of glycans by their receptors (lectins), which translate
the sugar-encoded information into effects. Duplication of ancestral genes and the following divergence of sequences account for the evolutionary dynamics in lectin families. Differences in gene number can even appear among closely related species. The adhesion/growth-regulatory galectins are selleck selected as an instructive example to trace the phylogenetic diversification in several animals, most of them popular models in developmental and tumor biology. Chicken galectins are identified as a low-level-complexity set, thus singled out for further detailed analysis. The various operative means for establishing protein diversity among the chicken galectins are delineated, and individual characteristics in expression profiles discerned. To apply
this galectin-fingerprinting approach in histopathology has potential for refining differential diagnosis and for obtaining prognostic assessments. On the grounds of in vitro work with tumor cells a strategically orchestrated co-regulation of galectin expression with presentation of cognate glycans is detected. This coordination epitomizes the far-reaching physiological significance of sugar coding.”
“An independent origin of the left vertebral artery from the aortic arch is the second most common aortic arch anomaly and occurs in 7% of otherwise healthy persons. Bilateral and independent origins of vertebral arteries are distinctly unusual. We present and illustrate such a case.”
“Zabott M. V., Pinto S. HDAC inhibitor B., Viott A. M., Tostes R. A., Bittencourt L. H. F. B., Konell A. L. & Gruchouskei L. 2012. [Occurrence of Dioctophyma renale in Galictis cuja.] Ocorrencia de Dioctophyma renale em
Galictis cuja. Pesquisa Veterinaria Brasileira 32(8): 786-788. Laboratorio de Parasitologia AZD1390 Veterinaria, Universidade Federal do Parana, Campus Palotina, Rua Pioneiro 2153, Palotina, PR 85950-00, Brazil. E-mail: [email protected]\n\nDioctophymosis is a parasitic disease caused by Dioctophyma renale (Goeze, 1782) with a worldwide occurrence and affects domestic animals as well as wildlife. In March 2010, a ferret adult male, Galictis cuja (Molina, 1782), found dead by trampling in the county of Guaira, state of Parana, Brazil, was necropsied in the Veterinary Pathology Laboratory at Campus Palotina, Federal University of Parana. The animal was in good nutritional condition and moderate autolysis. Three specimens of parasites were found in the abdominal cavity, but the kidneys were preserved. The parasites were fixed in acetic formaldehyde and sent to the Veterinary Laboratory of Parasitology, Campus Palotina, for identification. The parasites were identified as Dioctophyma renale, two females, one a 39cm long and 4mm wide and the other 16cm long and 4mm wide, and a male 16cm long and 3mm wide. This paper reports D.