PubMedCrossRef 9 Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wa

PubMedCrossRef 9. Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, et al.: COT

drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 2010,468(7326):968–972.PubMedCrossRef 10. Di-Poi N, Tan NS, Michalik L, Wahli W, Desvergne B: Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol Cell 2002,10(4):721–733.PubMedCrossRef 11. Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC: The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. selleck inhibitor Proc Natl Acad Sci U S A 1992,89(5):1875–1879.PubMedCrossRef 12. JSH-23 datasheet Yamasaki D, Kawabe N, Nakamura H, Tachibana K, Ishimoto K, Tanaka T, Aburatani H, Sakai J, Hamakubo T, Kodama T, et al.: Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARalpha-independent mechanisms. Eur J Cell Biol 2011,90(8):657–664.PubMedCrossRef 13. Hsin IL, Sheu GT, Chen HH, Chiu LY, Wang HD, Chan HW, Hsu CP, Ko JL: N-acetyl cysteine mitigates curcumin-mediated

telomerase inhibition through rescuing of Sp1 reduction in A549 cells. Mut Res 2010,688(1–2):72–77. 14. Srivastava RK, Rahman Q, Kashyap MP, Lohani M, Pant AB: Ameliorative effects of dimetylthiourea and N-acetylcysteine on nanoparticles induced ARS-1620 mw cyto-genotoxicity in human lung cancer cells-A549. PLoS One 2011,6(9):e25767.PubMedCrossRef 15. Peifer C, Alessi DR: Small-molecule inhibitors of PDK1. ChemMedChem 2008,3(12):1810–1838.PubMedCrossRef 16.

Pozzi A, Ibanez MR, Gatica AE, Yang S, Wei S, Mei S, Falck JR, Capdevila JH: Peroxisomal proliferator-activated Etofibrate receptor-alpha-dependent inhibition of endothelial cell proliferation and tumorigenesis. J Biol Chem 2007,282(24):17685–17695.PubMedCrossRef 17. Yokoyama Y, Xin B, Shigeto T, Umemoto M, Kasai-Sakamoto A, Futagami M, Tsuchida S, Al-Mulla F, Mizunuma H: Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer. Mol Cancer Ther 2007,6(4):1379–1386.PubMedCrossRef 18. Drukala J, Urbanska K, Wilk A, Grabacka M, Wybieralska E, Del Valle L, Madeja Z, Reiss K: ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro . Mol Cancer 2010, 9:159.PubMedCrossRef 19. Yu S, Levi L, Siegel R, Noy N: Retinoic acid induces neurogenesis by activating both retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta). J Biol Chem 2012,287(50):42195–42205.PubMedCrossRef 20. Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP: Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer. Am J Respir Cell Mol Biol 2008,39(6):689–696.PubMedCrossRef 21. Chung J, Irwin MS: Targeting the p53-family in cancer and chemosensitivity: triple threat.

Comments are closed.