Seventeen patients received radiotherapy alone and 25 had cisplatin-based chemotherapy additionally. The radiation dose to the primary tumour and involved nodes was 64-74 Gy.
Results: After a median follow-up of 60 months, the 5-year locoregional control, overall survival and disease-free survival rates were 87, 79 and 73%, respectively. More than 50% of the relapses (6/11) were distant metastases. Patients with N0-1 had a lower distant metastasis rate compared
with patients with N2-3, and the LCL161 solubility dmso TNM stage grouping was found to be a marginally important prognostic factor for disease-free survival. The addition of chemotherapy failed to be of therapeutic value. Acute and chronic toxicities were limited, consisting primarily of mucositis and xerostomia.
Conclusions:
The outcome of the present series was excellent, and matched well with other publications. ROCK inhibitor A high systemic failure remains a major obstacle to cure young NPC patients. More efforts should be made to improve both survival and quality of life. Shen, C. et at. (2009). Clinical Oncology 21, 617-622 (C) 2009 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.”
“The impact of laser pulsing on the field evaporation process is investigated for Al and W by pulsed laser atom probe tomography. Quantitative analysis reveals the influence on the spatial resolution of the peak temperature,reached by the specimen following light absorption from the laser pulse. It
is concluded that surface migration processes induce significant degradation of the lateral resolution, changing by 100% and 20%, respectively, for Al and W when the specimen temperature is increased from 4% to 7% of the material’s melting point, while the in-depth resolution is shown to remain nearly constant for both materials. (C) 2010 American Institute of Physics. [doi:10.1063/1.3462399]“
“Biopolymer nanocomposites are of great interest to the packaging industry as they can overcome the inferior properties find more of biopolymers compared with synthetic polymers. However, studies on property improvement have been inconclusive about optimum filler levels and mixing conditions. This article reports on a systematic study of effect on mechanical properties of varying melt mixing conditions and filler level in PLA organoclay composites. Samples were mixed in a batch mixer at various temperatures, times, and speeds, at three filler levels. Tensile properties were measured and morphology characterized using small angle X-ray scattering (SAXS). An empirical model was used to predict the optimum mixing conditions. Samples produced at those conditions had the highest modulus of all samples, 66% higher than the average. Samples with different filler levels were made at the optimum conditions and tested for modulus and morphology.