The aim of this study was to describe the follow up of patients with OGIB and a normal WCE examination, and assess the presence of rebleeding and possible associated factors. Methods: We analyzed 79 patients who consecutively underwent WCE examination for CHIR-99021 in vitro the study of OGIB between April 2006 and December 2011, whose results excluded potentially bleeding lesions. Pre- and post-WCE information was collected, including follow up interval and presence of rebleeding (defined as admission to the hospital for symptomatic

anemia, need for blood transfusion, decrease in hemoglobin value of >2 g/dL, or evidence of melena or hematochezia). Results: Of the 79 patients initially selected, 4 were excluded because there was no available information. Of the remainder,

61,3% were female and the mean age was 52 years. The indication for the examination was occult OGIB in 59 patients (78,7%) and overt OGIB in 16 patients (21,3%). 68 patients (90,7%) had hospital follow up, with 5-Fluoracil datasheet a mean follow up interval of 32 months. From these, 39 patients (57,4%) were posteriorly subjected to further investigation and a diagnosis was established in 11 of them. Rebleeding was documented in 16 (23,5%) of the 68 followed up patients, having occurred on average 15 months after WCE. From the analyzed factors (age, gender, indication for OGIB, past medical history, and hemoglobin value), only male gender was significantly associated with rebleeding (p = 0,007). Conclusion: Approximately a quarter of patients with OGIB and normal WCE examination will suffer from rebleeding, which is more significant in men. This result should imply a more regular medical surveillance, and possibly a more exhaustive attempt to clarify Astemizole the

etiology of the OGIB. Key Word(s): 1. capsule endoscopy; 2. follow-up; 3. rebleeding; 4. obscure bleeding; Presenting Author: DAE HWAN KANG Additional Authors: JOUNG BOOM HONG, HYUNG WOOK KIM, CHEOL WOONG CHOI, SU BUM PARK, BYUNG JUN SONG, YOUNG MI HONG, BYOUNG HOON JI, DONG JUN KIM, CHANG SEOK LEE Corresponding Author: DAE HWAN KANG Affiliations: Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital; Pusan National University Yangsan Hospital Objective: There is neither most suitable hemostatic method nor established procedure in non-variceal upper gastrointestinal bleeding (NVUGIB). The study aim was to compare endoscopic hemoclip placement with endoscopic coagulation method in non-variceal upper gastrointestinal bleeding. Also we tried to find the risk factor of recurrent bleeding. Methods: Design: Retrospective, single-center study.